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Featured Publications (5)

All Selected Publications

Prophylactic weekly efanesoctocog alfa versus standard-care factor VIII in people living with severe hemophilia A: a cost-effectiveness analysis

Ito S, Potnis KC, Harvey JP, Sra M, Bewersdorf JP, Bona RD, Krumholz HM, Cuker A, Pandya A, Goshua G.
Annals of Internal Medicine
2025
June
FEATURED
RECOGNITIONS:
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Gap: First conventional and distributional cost-effectiveness analysis in the care of people living with hemophilia A (Yale-HSPH-Mayo-Penn collaboration). ASH Abstract Achievement Award (S. Ito).

PRACTICAL IMPACT:

Cost-effectiveness of Lynch syndrome screening in colorectal cancer: universal germline vs sequential screening

Ito S, Xicola RM, Sra M, Potnis KC, Singh V, Gershkovich P, Stites E, Gibson J, Krumholz HM, Llor X, Goshua G
Clinical Gastroenterology & Hepatology
2025
April
FEATURED
RECOGNITIONS:
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Gap: Real-world diagnostic attrition leads to missed diagnoses of inherited Lynch syndrome in probands with colorectal cancer (CRC) and their relatives. Health economic rationale for upfront germline tumor testing in probands to improve population health.

PRACTICAL IMPACT:

Cost-effectiveness of ferritin screening thresholds for iron deficiency in reproductive-age women

Wang D, Sra M, Glaeser-Khan S, Wang DY, Moshashaian-Asl R, Ito S, Cuker A, Goshua G
American Journal of Hematology
2025
April
FEATURED
RECOGNITIONS:
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Gap: First cost-effectiveness analysis of ferritin screening thresholds in the care of people living with iron deficiency (Yale-Mayo-Vermont-Penn collaboration). 2024 ASH Press Program Selection, 2025 Highlights of ASH, ASH Abstract Achievement Award (D. Wang).

PRACTICAL IMPACT:

Cost-effectiveness of iptacopan for paroxysmal nocturnal hemoglobinuria

Ito S*, Chetlapalli K*, Wang D, Potnis KC, Richmond R, Krumholz H, Lee AI, Cuker A, Goshua G.
Blood
2025
January
FEATURED
RECOGNITIONS:
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Gap: Proximal complement inhibition is cost-saving for patients with suboptimal response on C5 inhibitor therapy in the United States and can be cost-saving in international jurisdictions (Penn-Yale collaboration).

PRACTICAL IMPACT:

Decreasing alloimmunization-specific mortality in sickle cell disease in the United States: Cost-effectiveness of a shared transfusion resource

Ito S, Pandya A, Hauser RG, Krishnamurti L, Stites E, Tormey C, Krumholz HM, Hendrickson JE, Goshua G
American Journal of Hematology
2024
April
FEATURED
RECOGNITIONS:
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Gap: Supporting the mission of the 501(c)(3) Alloantibody Exchange www.alloantibody.org. 2022 ASH Press Program Selection.

PRACTICAL IMPACT:
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